Research Interests

• Biochemistry and molecular genetics of wood decay fungi
• Synthesis of biofuels using enzymes and chemical catalysts
• Nanocatalysts for biomass conversion
• Natural product isolation and identification

Education

• University of Wisconsin, Madison, Ph.D.
• University of Wisconsin, Madison, B.S.

Professional Organizations

• American Society for Microbiology, Member
• Applied and Environmental Microbiology, Editorial Board

Featured Publications & Products

• Vanden Wymelenberg, Amber J.; Gaskell, Jill; Mozuch, Michael; Sabat, Grzegorz; Ralph, John; Skyba, Oleksandr; Mansfield, Shawn D; Blanchette, Robert A.; Martinez, Diego; Grigoriev, Igor; Kersten, Philip J; Cullen, Daniel. 2010. Comparative transcriptome and secretome analysis of wood decay fungi Postia placenta and Phanerochaete chrysosporium.
• Vanden Wymelenberg, Amber J.; Gaskell, Jill A.; Mozuch, Michael D.; Kersten, Philip J.; Sabat, Grzegorz; Martinez, Diego; Cullen, Daniel. 2009. Transcriptome and secretome analyses of Phanerochaete chrysosporium reveal complex patterns of gene expression.
• Pisanelli, Ines; Kujawa, Magdalena; Spadiut, Oliver; Kittl, Roman; Halada, Petr; Volc, Jindrich; Mozuch, Michael D.; Kersten, Philip; Haltrich, Dietmar; Peterbauer, Clemens. 2009. Pyranose 2-oxidase from Phanerochaete chrysosporium : expression in E. coli and biochemical characterization.
• Martinez, Diego; Challacombe, Jean; Morgenstern, Ingo; Hibbett, David; Schmoll, Monika; Kubicek, Christian P.; Ferreira, Patricia; Ruiz-Duenas, Francisco J.; Martinez, Angel T.; Kersten, Philip J.; Hammel, Kenneth E.; Gaskell, Jill A.; Cullen, Daniel. 2009. Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion.
• Vanden Wymelenberg, Amber; Sabat, Grzegorz; Mozuch, Michael; Kersten, Philip J.; Cullen, Dan; Blanchette, Robert A. 2006. Structure, organization, and transcriptional regulation of a family of copper radical oxidase genes in the lignin-degrading basidiomycete Phanerochaete chrysosporium.

Publications

• Iwata, Mana ; Gutiérrez, Ana ; Marques, Gisela ; Sabat, Grzegorz ; Kersten, Philip J.; Cullen, Daniel ; Bhatnagar, Jennifer M.; Yadav, Jagjit ; Lipzen, Anna ; Yoshinaga, Yuko ; Sharma, Aditi ; Adam, Catherine ; Daum, Christopher ; Ng, Vivian ; Grigoriev, Igor V; Hori, Chiaki . 2021. Omics analyses and biochemical study of Phlebiopsis gigantea elucidate its degradation strategy of wood extractives.
• Gaskell, Jill; Kersten, Phil; Larrondo, Luis F.; Canessa, Paulo; Martinez, Diego; Hibbett, David; Schmoll, Monika; Kubicek, Christian P.; Martinez, Angel T.; Yadav, Jagjit; Master, Emma; Magnuson, Jon Karl; Yaver, Debbie; Berka, Randy; Lail, Kathleen; Chen, Cindy; LaButti, Kurt; Nolan, Matt; Lipzen, Anna; Aerts, Andrea; Riley, Robert; Barry, Kerrie; Henrissat, Bernard; Blanchette, Robert; Grigoriev, Igor V.; Cullen, Dan. 2017. Draft genome sequence of a monokaryotic model brown-rot fungus Postia (Rhodonia) placenta SB12.
• Wang, Wangxia; Mozuch, Michael D.; Sabo, Ronald C.; Kersten, Philip; Zhu, Junyong; Jin, Yongcan. 2016. Endoglucanase post-milling treatment for producing cellulose nanofibers from bleached eucalyptus fibers by a supermasscolloider.
• Gaskell, Jill; Blanchette, Robert A.; Stewart, Philip E.; BonDurant, Sandra Splinter; Adams, Marie; Sabat, Grzegorz; Kersten, Philip; Cullen, Daniel. 2016. Transcriptome and secretome analyses of the wood decay fungus Wolfiporia cocos support alternative mechanisms of lignocellulose conversion.
• Mason, Charles J.; Klepzig, Kier D.; Kopper, Brian J.; Kersten, Philip J.; Illman, Barbara L.; Raffa, Kenneth F. 2015. Contrasting Patterns of Diterpene Acid Induction by Red Pine and White Spruce to Simulated Bark Beetle Attack, and Interspecific Differences in Sensitivity Among Fungal Associates.
• Wang, Wangxia; Sabo, Ronald C.; Mozuch, Michael D.; Kersten, Phil; Zhu, J. Y.; Jin, Yongcan. 2015. Physical and Mechanical Properties of Cellulose Nanofibril Films from Bleached Eucalyptus Pulp by Endoglucanase Treatment and Microfluidization.
• Wang, Wangxia; Mozuch, Michael D.; Sabo, Ronald C.; Kersten, Phil; Zhu, J.Y.; Jin, Yongcan. 2015. Production of cellulose nanofibrils from bleached eucalyptus fibers by hyperthermostable endoglucanase treatment and subsequent microfluidization.
• Hori, Chiaki; Ishida, Takuya; Igarashi, Kiyohiko; Samejima, Masahiro; Suzuki, Hitoshi; Master, Emma; Ferreira, Patricia; Ruiz-Duenas, Francisco J.; Held, Benjamin; Canessa, Paulo; Larrondo, Luis F.; Schmoll, Monika; Druzhinina, Irina S.; Kubicek, Christian P.; Gaskell, Jill A.; Kersten, Phil; St. John, Franz; Glasner, Jeremy; Sabat, Grzegorz; Bondurant, Sandra Splinter; Syed, Khajamohiddin; Yadav, Jagjit; Mgbeahuruike, Anthony C.; Kovalchuk, Andriy; Asiegbu, Fred O.; Lackner, Gerald; Hoffmeister, Dirk; Recoret, Jorge; Gutierrez, Ana; Sun, Hui; Lindquist, Erika; Barry, Kerrie; Riley, Robert; Grigoriev, Igor V.; Henrissat, Bernard; Kues, Ursula; Berka, Randy M.; Martinez, Angel T.; Covert, Sarah F.; Blanchette, Robert A.; Cullen, Daniel. 2014. Analysis of the Phlebiopsis gigantea Genome, Transcriptome and Secretome Provides Insight into Its Pioneer Colonization Strategies of Wood.
• Kersten, Phil; Cullen, Dan. 2014. Copper radical oxidases and related extracellular oxidoreductases of wood-decay Agaricomycetes.
• Gaskell, Jill; Marty, Amber; Mozuch, Michael; Kersten, Philip J.; Bondurant, Sandra Splinter; Sabat, Grzegorz; Azarpira, Ali; Ralph, John; Skyba, Oleksandr; Mansfield, Shawn D.; Blanchette, Robert A.; Cullen, Dan. 2014. Influence of Populus Genotype on Gene Expression by the Wood Decay Fungus Phanerochaete chrysosporium.
• Hori, Chiaki; Gaskell, Jill; Igarashi, Kiyohiko; Kersten, Phil; Mozuch, Michael; Samejima, Masahiro; Cullen, Dan. 2014. Temporal Alterations in the Secretome of the Selective Ligninolytic Fungus Ceriporipsis subvermispora during growth on Aspen Wood Reveal this Organism's Strategy for Degrading Lighnocellulose.
• Kersten, Phil; Cullen, Dan. 2013. Chapter 13: Recent Advances on the Genomics of Litter- and Soil-Inhabiting Agaricomycetes.
• Schwartz, Thomas J.; Goodman, Samuel M.; Osmundsen, Christian M.; Taarning, Esben; Mozuch, Michael D.; Gaskell, Jill; Cullen, Daniel; Kersten, Philip J.; Dumesic, James A. 2013. Integration of Chemical and Biological Catalysis: Production of Furylglycolic Acid from Glucose via Cortalcerone.
• Floudas, Dimitrios; Binder, Manfred; Riely, Robert; Barry, Kerrie; Blanchette, Robert A.; Henrissat, Bernard; Martínez, Angel T.; Otillar, Robert; Spatafora, Joseph W.; Yadav, Jagjit S.; Aerts, Andrea; Benoit, Isabelle; Boyd, Alex; Carlson, Alexis; Copeland, Alex; Coutinho, Pedro M.; deVries, Ronald P.; Ferreira, Patricia; Findley, Keisha; Foster, Brian; Gaskell, Jill; Glotzer, Dylan; Górecki, Pawe³; Heitman, Joseph; Hesse, Cedar; Hori, Chiaki; Igarashi, Kiyohiko; Jurgens, Joel A.; Kallen, Nathan; Kersten, Phil; Kohler, Annegret; Kües, Ursula; ArunKumar, T. K.; Kuo, Alan; LaButti, Kurt; Larrondo, Luis F.; Lindquist, Erika; Ling, Albee; Lombard, Vincent; Lucas, Susan; Lundell, Taina; Martin, Rachael; McLaughlin, David J.; Morgenstern, Ingo; Morin, Emanuelle; Murat, Claude; Nagy, Laszlo G.; Nolan, Matt; Ohm, Robin A.; Patyshakuliyeva, Aleksandrina; Rokas, Antonis; Ruiz-Dueñas, Francisco J.; Sabat, Grzegorz; Salamov, Asaf; Samejima, Masahiro; Schmutz, Jeremy; Slot, Jason C.; John, Franz St.; Stenlid, Jan; Sun, Hui; Sun, Sheng; Syed, Khajamohiddin; Tsang, Adrian; Wiebenga, Ad; Young, Darcy; Pisabarro, Antonio; Eastwood, Daniel C.; Martin, Francis; Cullen, Dan; Grigoriev, Igor V.; Hibbett, David S. 2012. The Paleozoic Origin of Enzymatic Lignin Decomposition Reconstructed from 31 Fungal Genomes.
• Vanden Wymelenberg, Amber; Gaskell, Jill; Mozuch, Michael; Splinter BonDurant, Sandra; Sabat, Grzegorz; Ralph, John; Skyba, Oleksandr; Mansfield, Shawn D.; Blanchette, Robert A.; Grigoriev, Igor; Kersten, Philip J.; Cullen, Daniel. 2011. Significant alteration of gene expression in wood decay fungi Postia placenta and Phanerochaete chrysosporium by plant species.
• Kopper, Brian J.; Illman, Barbara L.; Kersten, Philip J.; Klepzig, Kier D.; Raffa, Kenneth F. 2005. Effects of diterpene acids on components of a conifer bark beetle-fungal interaction : tolerance by Ips pini and sensitivity by its associate Ophiostoma ips.
• Kopper, Brian J.; Illman, Barbara L.; Kersten, Philip J.; Klepzig, Kier D.; Raffa, Kenneth F. 2005. Effects of diterpene acids on components of a conifer bark beetle fungal interaction: tolerance by Ips pini and sensitivity by its associate Ophiostoma ips.
• Vanden Wymelenberg, Amber J.; Sabat, Grzegorz; Martinez, Diego; Rajangam, Alex S.; Teeri, Tuula T.; Gaskell, Jill A.; Kersten, Philip J.; Cullen, Daniel. 2005. The Phanerochaete chrysosporium secretome : database predictions and initial mass spectrometry peptide identifications in cellulose-grown medium.
• de Koker, Theodorus H.; Mozuch, Michael D.; Cullen, Daniel; Gaskell, Jill; Kersten, Philip J. 2004. Isolation and purification of pyranose 2-oxidase from Phanerochaete chrysosporium and characterization of gene structure and regulation.
• de Koker, Theodorus H.; Mozuch, Michael D.; Kersten, Philip J. 2003. Analysis of D-glucose metabolism of wood decay fungi using 13C-NMR and 13C-labeled substrates.
• Mozuch, Michael D.; Kersten, Philip J. 2003. Identification of phanerosporic acid in birch degraded by Phanerochaete chrysosporium.
• de Koker, Theodorus H.; Kersten, Philip J. 2002. Characterization of wood decay enzymes by MALDI-MS for post-translational modification and gene identification..
• Urzua, Ulises; Kersten, Philip J.; Vicuna, Rafael. 1998. Kinetics of Mn3+-oxalate formation and decay in reactions catalyzed by manganese peroxidase of Ceriporiopsis subvermispora.
• Urzua, Ulises; Aguilar, Claudio; Kersten, Philip J.; Vicuna, Rafael. 1998. Oxalate metabolism in liquid cultures of Ceriporiopsis subvermispora : a possible pathway for extracellular H2O2 production.
• Stewart, Philip; Kersten, Philip; Vanden Wymelenberg, Amber J.; Gaskell, Jill A.; Cullen, Daniel. 1992. Lignin peroxidase gene family of Phanerochaete chrysosporium : complex regulation by carbon and nitrogen limitation and identification of a second dimorphic chromosome.

Research Highlights

Highlight	Title	Year
FPL-2013-140	Enzyme Combo Results in Bioplastics Composite Developing bioplastics as a means of moving away from non-renewable, petroleum-based products has many economic and environmental benefits. Rese ...	2013
FPL-2016-57	Improving the Hydrolysis and Fibrillation of Wood Into Cellulose Nanomaterials Cellulose nanomaterials have been receiving an increasing amount of interest from both the scientific and industrial communities because of thei ...	2016