Fire prevention has the promise of reducing overall expenditures and damages from wildfires. Prevention program elements can include burn permits, public service programs or announcements, outreach efforts to schools, youth groups, equipment operators, and law enforcement. In this interagency collaboration, Forest Service scientists Karen Abt and Jeffrey Prestemon worked with tribal wildfire prevention specialists Samuel Scranton, the lead fire prevention officer for the Bureau of Indian Affairs, and David Butry of the National Institute of Standards and Technology. The scientists found that prevention activities on 17 tribal land units led to significant reductions in wildfires caused by escaped campfires, juveniles, fire use, and equipment. The results of the study indicate that the initiation of a program leads to suppression spending avoidance that exceeds the prevention program costs from between 5 and 38 fold. Results can therefore be used to support Bureau of Indian Affairs and other agencies' decisions about the important potential role of fire prevention in the suite of management actions to reduce overall negative impacts from wildfires.