Search
US Forest Service Research & Development
Contact Information
  • US Forest Service Research & Development
  • 1400 Independence Ave., SW
  • Washington, D.C. 20250-0003
  • 800-832-1355
You are here: Home / People / Profile

Profile


VIVO Logo

Daniel Cullen

Research Microbiologist
One Gifford Pinchot Drive
Madison, WI 53726-2398
Phone: 608-231-9468


Current Research

Our main goal is to develop a fundamental understanding of the molecular genetics and physiology of wood decay fungi, particularly as it relates to mechanisms of lignocelulose degradation. Within this broad area, my labs seeks (a) to elucidate the underlying genetics of lignin degrading white rot fungi including the number, structure, organization and regulation of genes relevant to lignocellulose conversions, (b) to advance our understanding of the biochemistry of essential enzymes, (c) to fully develop fundamental genetics of a representative brown rot fungi, and (d) to advance our understanding of gene function via high throughput approaches suitable for whole genomes.Genome investigations have focused principally on the white rot fungus Phanerochaete chrysosporium and the brown rot fungus Postia placenta. However, our collaborations with the Department of Energy's Joint Genome Institute have recently expanded to include the related white rot fungi, Ceriporiopsis subvermispora (http://www.jgi.doe.gov/sequencing/why/csubvermispora.html) and Phlebiopsis gigantea. In addition to their central role in carbon cycling, these wood decay fungi are representative of the basidiomycetes, a broad taxa including mycorrhizae, plant, human and animal pathogens, edible forms, and various saprophytes. Accordingly, my lab also contributes to large international teams working on the genomes of Pleurotus ostreatus (http://genome.jgi-psf.org/PleosPC15_1/PleosPC15_1.info.html ), Heterobasidion annosum (http://genome.jgi-psf.org/Hetan1/Hetan1.info.html ), Agaricus bisporus (http://www.jgi.doe.gov/sequencing/why/99189.html ), Serpula lacrymans, and Phanerochaete carnosa.

Research Interests

  • Molecular genetics of filamentous fungi
  • High throughput analysis of fungal transcriptomes and proteomes
  • Mechanisms of wood decay
  • Enzyme discovery for applications in bioenergy, bioremediation, and pulp and paper processing

Education

  • University of Wisconsin, Madison, Ph.D. , 1981
  • State University of New York at Stony Brook, BS , 1975

Professional Organizations

  • American Society for Microbiology, Member
  • Applied and Environmental Microbiology, Editor
  • National Science Foundation and Department of Energy, Advisory Panels

Featured Publications & Products

Publications & Products

Research Highlights

HighlightTitleYear


FPL-2013-150
Common Button Mushroom Studied for Key Role in Recycling Carbon

Recent genome studies of Agaricus reveal specialized adaptations to litter- and soil-rich environments which may be used to remediate contaminat ...

2013


FPL-2010-030
Fast Forward' Genetics for Renewable Fuels

Researchers at the Forest Products Laboratory used mutagenesis, strain selection and genetic manipulation over a period of seven years to develo ...

2010


FPL-2012-09
Hidden Lives of Wood Decay Fungi Uncovered by Genome Sequencing

The decoded genomes of 12 species reveal a complex repertoire of proteins involved in the deconstruction of key polymers within wood cell walls

2012


FPL-2013-151
Research Demystifies Wood Decaying Fungi

Newly sequenced fungal genomes provide insight into the enzymatic conversion of wood into high value products.

2013


Last updated on : 11/26/2014